Residence Inn Portsmouth Downtown/Waterfront is located in the heart of Downtown Portsmouth and lies adjacent to Portsmouth Harbor Events & Conference Center and is a LEED Environmental Certified Hotel in the Seacoast region. Located just footsteps away from the Piscataqua River, Isles of Shoals Steamship Company and Strawbery Banke, a wide variety of shopping boutiques, area restaurants, live theaters, art galleries, historic homes and waterfront gardens are at your fingertips. Our all-suite, extended stay hotel is pet-friendly, offering such amenities as a heated indoor pool, fitness center, on-site bar featuring lighter fare, evening socials and complimentary hot breakfast. This Downtown Seacoast Hotel allows for easy access to NH & ME beaches, the University of New Hampshire and Kittery Shopping Outlets, as well as major area corporations. Just one hour north of Boston and south of Portland, Maine, our well-appointed Portsmouth NH hotel offers a scenic yet convenient setting for both business and leisure.